Monday, 30 October 2017

BioMaths Colloquium - 20/10/2017

BioMaths Colloquium Series - 2017/18

20 October 2017 - 3pm Maths Seminar Room

(room 224 Talbot Building 2nd floor)

Patterns, cellular movement and brain tumours

Dr Thomas Woolley

(Department of Mathematics, Cardiff UniversityUK) 

Our first BioMaths Colloquium Series for the 2017/18 academic year features a seminar by Dr Thomas Woolley from the School of Mathematics at University of Cardiff (UK).

I present three pieces of work that illustrate the power of mathematics as a tool for understanding biology. Although the applications appear to be disparate the underlying mathematics is very similar. I begin by looking at theoretical and experimental pattern formation, with emphasis on whisker formation in mice. Here, reaction-diffusion equations are used to provide insights into how the wavelength of the whiskers are controlled. 
   Next, I consider the phenomena of blebbing cells. Initially, I use a diffusion equation to understand the motion of muscle stem cells and illustrate how young cells fundamentally move differently to old cells. This is then extended to include solid mechanics, which allows us to link the structural properties of the cell to their motion. 
   Finally, reaction-diffusion equations are used to understand the formation of brain tumours. Critically, the cells move at different speeds in white and grey matter, including this information can lead to very different migration patterns of the tumours. 

The discussions will continue over biscuits and tea/coffee after the seminar. 
Hope to see many of you!

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